Objective: The plant Ocimum basilicum belonging to family Lamiaceae is used in Skin disease, eye disease, fever and wounds. The present study was carried out to evaluate the effect of Ocimum basilicum whole plant (ethanolic and aqueous extract p.o.) on gastric and duodenal ulceration. Materials and Methods: The study was carried out on duodenal ulceration models such as cysteamine induced ulcer...

The chemical compositions of essential oils obtained from Ocimum basilicum var. thyrsiflora (1.39 % dry weight) and Ocimum basilicum (0.61 %) were analyzed by GC–MS. Seventy-three constituents representing 99.64 % of the chromatographic peak area were obtained in the O. basilicum var. thyrsiflora oil, whereas 80 constituents representing 91.11 % observed in the essential oil of O. basilicum wer...

Ursolic acid is a very important compound due to its biological potential as an anti-inflammatory, trypanocidal, antirheumatic, antiviral, antioxidant and antitumoral agent. This study presents the HPLC analysis of ursolic acid (UA) content in eight different Ocimum species: O. americanum L., O. basilicum L, O. basilicum var purpurascens Benth, O. basilicum var. minimum L, O. gratissimum L, O. ...

CONTEXT Ocimum basilicum L. (Lamiaceae), popularly known as basil, is part of a group of medicinal plants widely used in cooking and known for its beneficial health properties, possessing significant antioxidant effects, antinociceptive, and others. OBJECTIVE The objective of this study is to determine the pharmacological effects produced on the bacterial strains Staphylococcus aureus and Pse...

This research highlights the chemical composition, antioxidant, anti-inflammatory and anti-proliferative activities of essential oils from leaves of Ocimum basilicum, Ocimum americanum, Hyptis spicigera, Lippia multiflora, Ageratum conyzoides, Eucalyptus camaldulensis and Zingiber officinale. Essential oils were analyzed by gas chromatography-mass spectrometry and gas chromatography-flame ioniz...

AIM To evaluate the phenolics composition and inhibitory effect of the leaves extracts of Ocimum basilicum and Ocimum gratissimum on two key enzymes (pancreatic lipase [PL] and angiotensin 1-converting enzyme [ACE]) involved in obesity and hypertension in vitro. MATERIALS AND METHODS The phenolics (flavonoids and phenolic acids) were quantified using high-performance liquid chromatography cou...

The chemical constituents of leaves, inflorescence, and flowers from Ocimum basilicum (Thai basil) and Ocimum sanctum (Holy basil) were analysed by gas chromatography-mass spectrometry. The chemical compounds were extracted by hydrodistillation, headspace-solid phase microextraction, and solvent extraction.  The main constituents of Ocimum basilicum were identified to consist of estragole (...

This study sought to carry out a screening of the polyphenols from the aerial parts of four samples of Ocimum basilicum. HPLC-MS method was used to investigate the presence of phenolic compounds in the studied samples; caftaric, cafeic, chlorogenic, p-coumaric acids and rutin were identified. The total polyphenolic content was determined by using the Folin-Ciocalteu reagent, the flavonoid and t...

In this study, the in vitro anticholinesterase activity of the volatile oils of both O. basilicum and O. africanum was investigated and both samples showed significant activity. The major constituents of the two oils were isolated using several column chromatographies. Linalool, 1,8-cineol and eugenol were isolated from the volatile oil of O. basilicum and camphor was isolated from the volatile...